Can I leave RENA Crystals in the water when medicating my fish tank?

I am treating my fish tank, I know that when you treat a tank you usually remove the carbon from the filter. Does the same rule apply to the RENA crystal, or can I leave it in without affecting the potency of the medicine?

A: I do believe you should remove any chemical filtration if you are medicating the tank. However, the best source for this information is the manufacturer, Mars Fishcare.